All of the above procedures apply to studies involving human subjects. Allowing children in the foster care system to take part in clinical trials or other research is not prohibited, and may occur in accordance with 45 CFR Part 46 if the Division deems that the child(ren) will ultimately benefit. Research involving human subjects includes data collection through intervention or interaction with the individual or identifiable private information. In addition, an independent advocate is required to be appointed for the child and proper consent from a guardian applies to clinical trials involving new drugs and for any research setting in which children in foster care are subjects.